Vitamin C is a well known antioxidant nutrient with a variety of features within the human physique, together with collagen synthesis, wound therapeutic, protein metabolism, synthesis of neurotransmitters and L-carnitine, and immune system assist.
Although it’s not terribly tough to acquire satisfactory quantities of this nutrient from a complete meals, nutrient-dense food regimen, typically somewhat additional could be warranted.
So, you determine to hunt out a top quality vitamin C complement, solely to find that there are a couple of gazillion choices to select from at your native grocery or well being meals retailer.
The next article seeks to make clear somewhat bit concerning the types, sources, supply strategies, and dosages of vitamin C dietary supplements available on the market as a way to make knowledgeable selections for your self or your shoppers.
First, let’s have a look at the commonest types and sources of vitamin C dietary supplements you may encounter.
Ascorbic Acid
Vitamin C and L-ascorbic acid are thought-about to be synonymous. Most dietary supplements you’ll encounter include ascorbic acid from artificial or pure sources, that are usually equivalent within the molecule’s form and organic exercise.
The molecule ascorbic acid may be oriented in two methods: with the atoms rotating to the left (L-ascorbic acid) or rotating to the precise (D-ascorbic acid). What’s necessary to know is that in nature, vegetation, micro organism, and animals with the power to provide ascorbic acid that rotates to the left. People, who can’t produce ascorbic acid, additionally use the L type.
Pure ascorbic acid happens in meals, significantly vegetables and fruit like strawberries, kiwi, papaya, citrus fruits, and all sorts of peppers. For “pure” vitamin C dietary supplements, ascorbic acid is made by permitting sure micro organism, like Saccharomyces cerevisiae, to ferment a sugar substrate, like glucose or sorbitol.
Artificial ascorbic acid is often produced industrially by a way referred to as the Reichstein course of, which makes use of chemical and microbial steps to transform D-glucose to L-ascorbic acid. Glucose for artificial ascorbic acid usually comes from corn, which may be closely processed and is commonly genetically modified, so think about the standard and supply of the components when selecting this type of supplementation.
Because the identify suggests, ascorbic acid is acidic. Due to this fact, some folks could also be delicate to giant doses, maybe experiencing gastrointestinal discomfort or diarrhea. If this can be a concern, the following type could be gentler on the intestine.
Mineral Ascorbates
Mineral ascorbates are a salt consisting of an ascorbate ion (unfavorable cost) certain to a mineral ion (optimistic cost). Most frequently, the mineral utilized in ascorbates is sodium or calcium. Different ascorbates could include potassium, magnesium, zinc, molybdenum, chromium, manganese, or a mix of those.
Ascorbates are ascorbic acid minus an acidic hydrogen atom. Shedding the hydrogen makes this type of vitamin C impartial in pH, due to this fact mineral ascorbates are often known as buffered vitamin C. They’re shaped by reacting ascorbic acid with mineral carbonates, like calcium carbonate or sodium bicarbonate.
An necessary factor to recollect when selecting a vitamin C complement on this type is that the mineral can also be absorbed, and contributes to your every day calcium, or different mineral, consumption.
Vitamin C with Bioflavonoids
In nature, vitamin C comes packaged in with a complete lot of different vitamins, together with fiber, phytonutrients, and different nutritional vitamins and minerals. Some vitamin C dietary supplements search to imitate nature’s packaging by together with polyphenolic compounds present in vegetation, referred to as bioflavonoids.
Regardless of appreciable analysis, it’s nonetheless unclear whether or not the addition of bioflavonoids will increase the bioavailability of vitamin C, although phytonutrients definitely have their very own advantages, together with being antioxidants. The idea is that when bioflavonoids are taken with vitamin C, bioflavonoids can neutralize free radicals encountered within the digestive tract, thus sparing vitamin C to be extra accessible for absorption and use elsewhere within the physique. Bioflavonoids themselves don’t take up into the bloodstream very properly, so it’s tough to measure their availability within the physique, not to mention their results on vitamin C absorption.
Dietary supplements containing bioflavonoids are sometimes sourced from complete meals wealthy in vitamin C and bioflavonoids, corresponding to citrus fruits, acerola cherry, rose hips, and different vegetables and fruit. Some dietary supplements are marketed as “uncooked”, which means they’re solely sourced from pure components (together with ascorbic acid derived from bacterial fermentation) and infrequently include enzymes and probiotics.
Mineral Ascorbates + Metabolites
One more type of vitamin C complement is patented underneath the identify Ester-CⓇ. Along with mineral ascorbates, Ester-CⓇ additionally accommodates vitamin C metabolites, together with dehydroascorbic acid, which is oxidized vitamin C, and different compounds corresponding to calcium threonate, xylonate, and lyxonate.
You could be questioning why oxidized vitamin C is a good suggestion to take as a complement. Why is it helpful to take an antioxidant that’s already oxidized?
The reply is within the absorption. Oxidized ascorbic acid enters cells utilizing a distinct kind of protein transporter within the intestines, giving this molecule an alternate entry level into cells than ascorbic acid. As soon as contained in the cells, the physique reduces dehydroascorbic acid to its helpful type, and voilà, the antioxidant lives on to neutralize one other free radical.
Liposomal Vitamin C
Vitamin C is a water-soluble vitamin. As such, it’s not saved in cells and tissues in any considerable quantity, so constant every day consumption is necessary. As well as, it requires somewhat little bit of assist from protein transporters to cross the lipid barrier of cell membranes (extra on these protein transporters later).
To bypass these solubility points, some vitamin C dietary supplements are made to encompass water-soluble ascorbic acid in tiny fat-soluble packages, referred to as liposomes. Liposomal vitamin C is designed to include fat-soluble particles and water-soluble vitamin C collectively as a way to enhance stability and facilitate entry into the cells.
Supplemental Vitamin C Supply, Dosage, and Absorption
All through these descriptions of the assorted types of vitamin C dietary supplements, I’ve talked about the usage of protein transporters a couple of occasions in reference to how this vitamin will get inside cells.
Whether or not from meals or dietary supplements, the vast majority of vitamin C is absorbed with the assistance of sodium-dependent energetic transporters, that are proteins that assist the water-soluble molecule cross the lipid-based membrane surrounding cells. Most vitamin C dietary supplements – liquids, powders, drugs, and capsules – are ingested orally and absorbed on this means.
Many years of analysis verify that these proteins turn into saturated at excessive concentrations of vitamin C, with absorption reducing at and above 200 mg. Contemplating this proof, a number of small doses of supplemental vitamin C could also be more practical than a single giant dose for absorption and assimilation.
As already talked about, oxidized vitamin C, dehydroascorbic acid, has one other entry level. It enters cells with the assistance of facilitated glucose transporters, one other kind of protein. Vitamin C competes with glucose for entry to those proteins, so excessive concentrations of sugar block dehydroascorbic acid from coming into cells on this means.
Liposomal vitamin C supplements bypass the necessity for these transporters, because the vitamin is encased in lipid compartments that may passively diffuse throughout cell membranes. Any such complement is promising in that it would obtain greater circulating concentrations of vitamin C than typical oral formulations.
Beneficial Vitamin C Intakes and Different Concerns
The advisable dietary allowance (RDA) for vitamin C is as follows:
- 90 mg/day for males
- 75 mg/day for girls
- People who smoke could require a further 35 mg/day
Different components which will improve the necessity for added vitamin C embody being pregnant, lactation, sure drugs, wound healing, diets of poor dietary high quality, and stress.
The tolerable higher restrict (UL) is 2000 mg/day, which is the very best consumption that’s more likely to produce no hostile well being results within the basic inhabitants.
Individuals with excessive iron ranges must be cautious about vitamin C supplementation, as vitamin C will increase the absorption of iron.
A Holistic Strategy to Vitamin C Adequacy
As nutrition therapy practitioners, we acknowledge that dietary supplements are merely a device to enhance nutrient ranges on high of a powerful foundational food regimen based mostly on complete meals. Vitamin C-rich meals convey extra advantages through the synergistic results of an abundance of vitamins, corresponding to macronutrients and micronutrients together with nutritional vitamins, minerals, and bioflavonoids.
To shut, I’ll share a easy infusion I discovered from the director of the Vitamin Remedy Institute, Dianne Koehler, in one of many lessons supplied as a part of the Nutrition Therapist Master Certification Program.
To make the infusion you will want:
- Dried, coarsely floor rose hips
- Barely beneath boiling temperature water
Pour 8-12 ounces of sizzling water over a couple of teaspoon of coarsely floor rose hips. Permit it to infuse for 5-10 minutes. Pressure and luxuriate in.
As well as, you possibly can grind rose hips to make use of as a substitute for vitamin C powder. Rose hips are an awesome supply of vitamin C, vitamin E, important fatty acids, and bioflavonoids.
I hope this text shed some gentle on the sophisticated world of vitamin dietary supplements. In case you’d wish to be taught extra, think about enrolling on the Nutrition Therapy Institute to turn into a Nutrition Therapist Master!
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In regards to the creator: Karyn Lane is a latest graduate of NTI’s Nutrition Therapist Master Program. She finds her chemistry diploma a great tool in her examine of holistic vitamin. She additionally likes to deal with her kitchen as a laboratory for brand new recipes and cooking methods. You may observe her on Instagram @karyn.aka.klaryn.
About Vitamin Remedy Institute’s Holistic Vitamin Certification
Vitamin Remedy Institute (NTI) is a frontrunner in holistic vitamin schooling since 1999. NTI gives on-line and in-person vitamin course choices to assist college students obtain thriving careers as holistic vitamin therapists. Serious about beginning our holistic vitamin programs and incomes your holistic vitamin certification? Attend an informational webinar to be taught extra!
Photos:
Image by JerzyGorecki from Pixabay
Image by Peggychoucair from Pixabay
Yellow, red and green bell peppers. by Nick Fewings on Unsplash